翻訳と辞書 Words near each other ・ Genome diversity and karyotype evolution of mammals ・ Genome editing ・ Genome engineering ・ Genome evolution ・ Genome Hazard ・ Genome instability ・ Genome Institute of Singapore ・ Genome project ・ Genome Reference Consortium ・ Genome Research ・ Genome Research Foundation ・ Genome size ・ Genome survey sequence ・ Genome Therapeutics Corporation ・ Genome Valley ・ Genome-based peptide fingerprint scanning ・ Genome-wide association study ・ Genome@home ・ Genomes OnLine Database ・ Genomespace ・ Genomic and Medical Data ・ Genomic convergence ・ Genomic counseling ・ Genomic DNA ・ Genomic imprinting ・ Genomic island ・ Genomic library ・ Genomic Medicine Institute ・ Genomic organization ・ Genomic phylostratigraphy Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Genome-based peptide fingerprint scanning ： ウィキペディア英語版 Genome-based peptide fingerprint scanning Genome-based peptide fingerprint scanning (GFS) is a system in bioinformatics analysis that attempts to identify the genomic origin (that is, what species they come from) of sample proteins by scanning their peptide-mass fingerprint against the theoretical translation and proteolytic digest of an entire genome. This method is an improvement from previous methods because it compares the peptide fingerprints to an entire genome instead of comparing it to an already annotated genome. This improvement has the potential to improve genome annotation and identify proteins with incorrect or missing annotations. == History and Background == GFS was designed by Michael C. Giddings (University of North Carolina, Chapel Hill) et al., and released in 2003. Giddings expanded the algorithms for GFS from earlier ideas. Two papers were published in 1993 explaining the techniques used to identify proteins in sequence databases. These methods determined the mass of peptides using mass spectrometry, and then used the mass to search protein databases to identify the proteins In 1999 a more complex program was released called Mascot that integrated three types of protein/database searches: peptide molecular weights, tandem mass spectrometry from one or more peptide, and combination mass data with amino acid sequence. The fallback with this widely used program is that it is unable to detect alternative splice sites that are not currently annotated, and it not usually able to find proteins that have not been annotated. Giddings built upon these sources to create GFS which would compare peptide mass data to entire genomes to identify the proteins. Giddings system is able to find new annotations of genes that have not been found, such as undocumented genes and undocumented alternative splice sites. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Genome-based peptide fingerprint scanning」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.